Wild Arms: Twilight Venom

This anime is based on a playstation game under the same title. The story is about four people who travel the desolated land of Filgaea and carve themselves a legendary story while they're at it. These adventurers are Sheyenne Rainstorm, a gunslinger who holds the legendary weapon called ARMs; Kiel Aromax, a scientist who looks like he should be carrying a sword; Roleta Oratorio the Crest Sorceress, a magic-user who uses cards called Crests to cast spells; and Mirabelle Graceland, one of the Noble Red, which are a family of vampiric creatures who live alongside human beings They also travel with cute little intelligent furry things, from the Popepi Pipepo Tribe, named Isaac and Jerusha. (Source: AniDB)Wild Arms exploits the tales of Sheyenne Rainstorm, a deadly gunslinger trapped in the body of a 10-year old boy. Together with bandit Kiel Aronakus, card-throwing dame Loretta Oratorio, vampire girl Mirabelle Graceland and a weird creature named Jerusha, Sheyenne embarks on a long journey to find out about his lost past and figure out who placed him in his current body.