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Once, vampires and humans lived in harmony. Now, a young girl and a vampire queen will search for that Paradise once again. In the divided world of the future, two girls want to do the forbidden: the human wants to play the violin, and the vampire wants to see a wider world. (Source: Netflix, edited)

Kujo Jotaro is a normal, popular Japanese high-schooler, until he thinks that he is possessed by a spirit, and locks himself in prison. After seeing his grandfather, Joseph Joestar, and fighting Joseph's friend Muhammad Abdul, Jotaro learns that the "Spirit" is actually Star Platinum, his Stand, or fighting energy given a semi-solid form. Later, his mother gains a Stand, and becomes sick. Jotaro learns that it is because the vampire Dio Brando has been revived 100 years after his defeat to Jonathan Joestar, Jotaro's great-great-grandfather. Jotaro decides to join Joseph and Abdul in a trip to Egypt to defeat Dio once and for all.

Vampires are known to have many weaknesses that balance out their incredible power, but the vampire lord Draluc happens to be weak to pretty much anything. The vampire hunter Ronald receives a job to infiltrate the castle of the so-called "Invincible Progenitor" and rescue a woman's son from the monster within. But upon arriving, he is dumbfounded to discover that the vampire quickly turns to ash by something as trivial as a clap of his hands! Moreover, the child he was sent to save had merely wandered in to play the vampire lord's video games while he slept! In a disastrous turn of events, Draluc's castle is destroyed, and the fragile vampire decides to move in with the hunter who has only just defeated him. Ronald, Draluc, and the vampire's pet armadillo John form quite the eccentric team as they are forced to work together while fending off Ronald's violent editor, the lesser vampires plaguing the city, and even their fellow vampire hunters. [Written by MAL Rewrite]